Troubleshooting to Calculate Home Adjustments

Cut a one layer rectangle opening without Cutting the Outside. 

From the front of the mat, measure the Right and Bottom borders from the inside of the bevel to the edge of the mat.

Enter those values into the Act Right Border (Actual Right Border) and Act Btm Border (Actual Bottom Border) fields.  

Click on the Calc Home Adjustments button to recalculate and adjust the Horizontal and Vertical positions.

Do a test cut to confirm that it is correct and readjust if necessary.